Adventures Of Superman #591 2001

Adventures Of Superman #591, "Infestation" Part 2, finds Superman returning home after seemingly vanquishing the Viroxx virus. However, the insidious pathogen strikes at his most vulnerable point: Lois Lane. Superman is horrified as his wife is transformed into a mindless anti-body, becoming an unwilling instrument of Viroxx, dispatched to infect other worlds. This issue presents a profound and personal crisis for the Man of Steel, forcing him to confront a devastating threat to his beloved.