Deadpool #37 2014

Deadpool #37 (Marvel, 2000) sees Wade Wilson manipulated by Loki into attempting to wield Mjolnir, believing it will free Mistress Death. Upon realizing Loki's deception, Deadpool turns against him, only to be cursed. This issue is highly notable to collectors as it features a pivotal moment where Loki explicitly confirms to Deadpool that he is a fictional character. This event solidifies Deadpool's iconic fourth-wall breaking and meta-awareness as a fundamental aspect of his personality and worldview.