Deadpool #45 2011

Deadpool #45, from the 2008 Marvel series, introduces the first appearance of Evil Deadpool. The story delves into a bizarre scenario where Deadpool's discarded, frozen body parts thaw and reanimate, fusing into a monstrous, malevolent new entity. This issue is highly notable to collectors for marking the debut of Evil Deadpool, a significant character development that adds a dark twist to the Merc with a Mouth's chaotic world. It's a key moment in the character's modern history.