Deadpool Kills The Marvel Universe Again #2 2017

Deadpool Kills The Marvel Universe Again #2, published by Marvel in 2017, continues the Merc with a Mouth's new rampage across a fresh alternate reality. As heroes like Punisher, Cable, and Jessica Jones investigate the escalating murders, Deadpool eliminates Eddie Brock (Venom), Miles Morales (Spider-Man), Spider-Woman, and Miguel O'Hara (Spider-Man 2099). The issue also sees the Punisher killed by his own sabotaged weapon. This issue is notable for collectors due to the significant deaths of multiple fan-favorite characters.