Detective Comics #746 2000

Detective Comics #746 concludes the "Evolution" storyline as Batman races to stop Whisper A'Daire from unleashing a life-altering serum upon Gotham's crime families. The serum promises extended life but carries unpredictable animalistic side effects, threatening chaos. This issue is notable for collectors as it features the first appearance of Pasquale "Junior" Galante and introduces "The Jacobian," a new backup series, marking a significant moment in the title's history.