Detective Comics #780 2003

Detective Comics #780 presents two distinct narratives. In "Dead Reckoning, Part Four," Batman investigates a killer dubbed "The Charlatan," whose spree targets Arkham Asylum inmates. The Mad Hatter is poisoned, prompting Batman and Catwoman to question the Riddler, who uncovers a past conspiracy by various rogues to eliminate Batman. This leads Batman to plan an interrogation with the Joker. The issue also concludes the "Spore" storyline, where a Nanobat successfully eradicates an extraterrestrial infection from Batman, ultimately safeguarding Earth. This comic is notable for its progression of the "Dead Reckoning" arc and the finale of the "Spore" saga.